Lesson 8 of 8
How a moat dies
Four recorded endings. Bristol Myers Squibb's Revlimid fell 49 percent in 2025, and the 1991 Berkshire letter records a different one while it happened.
By Javier Sanz
Founder of ValueScreener. Built Ninety Nine, a securities services provider, and sold it to a tier-one global bank; ran operations and internationalization at Alpaca, the brokerage API.
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In one minute
- The four recorded endings are substitution, the expiry of a legal exclusivity, the loss of the scale the advantage rested on, and the owner's own decisions.
- Exclusivity ending is the only one with a date on it: Bristol Myers Squibb's Revlimid revenue fell 49 percent to 2,951 million dollars in 2025, and two other legacy products fell 62 and 58 percent.
- The 1991 Berkshire letter records substitution as it was happening, and its own arithmetic shows the valuation consequence.
A moat rarely fails suddenly. It fails in one of four ways, and three of them are visible in disclosures years before they show up in a margin.
Bristol Myers Squibb legacy product revenue, 2025 against 2024
| Product | 2025 | 2024 | Change |
|---|---|---|---|
| Revlimid | 2,951 | 5,773 | -49% |
| Pomalyst and Imnovid | 2,733 | 3,545 | -23% |
| Sprycel | 493 | 1,286 | -62% |
| Abraxane | 368 | 875 | -58% |
| Total revenues | 48,194 | 48,300 | 0% |
Ending one: exclusivity runs out
A patent has an expiry date, published years in advance, and it is the only moat failure that arrives on a schedule. The revenue decline that follows is not gradual.
The Bristol Myers Squibb figures above are what that looks like in a filing. Revlimid revenue of 2,951 million dollars in 2025 against 5,773 million in 2024. Sprycel at 493 million against 1,286 million. Abraxane at 368 million against 875 million. Total revenues across the company were essentially flat at 48,194 million against 48,300 million, because other products grew into the gap.
The aspartame case makes the same point from the other side: after the European patent expired in 1987 and a competitor entered, the price of aspartame fell 60 percent, and the entrant lost money doing it.
Ending two: substitution
The 1991 Berkshire letter documents one in progress. It observes that the economic strength of media businesses was eroding as retailing patterns changed and advertising and entertainment choices proliferated, and that newspaper, television and magazine properties had begun to resemble businesses more than franchises in their economic behaviour.
Note what changed and what did not. The newspapers still printed, the advertisers still advertised, and revenue in the year was not the evidence. The evidence was that customers had acquired alternatives, which meant the second of the three franchise conditions, that customers believe there is no close substitute, had stopped holding.
And the letter prices it: a property valued as a growing perpetuity at 25 times after-tax earnings becomes, on a bob-around assumption, worth 10 times. The valuation consequence of a substitution arrives long before the revenue consequence does.
Ending three: the scale stops mattering
A scale advantage rests on a market being the unit of competition. When that stops, the share that created the advantage stops producing anything.
This ending is the hardest to see because nothing in the company's own numbers changes at first. What changes is that a competitor can now reach the customer without paying the cost the incumbent's share was spreading.
Ending four: the owner's own decisions
An acquisition into an adjacent business with no barrier. A price increase that teaches customers to look elsewhere. Cost cutting into the thing the customer was paying for. Extending the brand until it stops meaning anything specific.
This one leaves the clearest trail, because every part of it is disclosed: acquisitions in the business combination note, pricing in the revenue discussion, and cost cutting in the expense lines. It is also the only ending where the company chose it.
Check yourself
Which moat ending arrives on a published schedule?
- Substitution
- The expiry of a legal exclusivity, whose date is public years in advance
- A loss of scale
Show the answer
Answer: B.
A patent expiry is dated. Bristol Myers Squibb's Revlimid revenue fell 49 percent to 2,951 million dollars in 2025, alongside declines of 62 and 58 percent in two other legacy products.What did the 1991 Berkshire letter identify as the change in media businesses?
- A fall in advertising volumes that year
- That customers had acquired alternatives, so the properties began to resemble businesses rather than franchises
- Regulatory price controls
Show the answer
Answer: B.
The letter attributes it to changing retailing patterns and proliferating advertising and entertainment choices, which is the second franchise condition ceasing to hold.Why is the substitution ending expensive before it is visible in revenue?
- Because customers leave immediately
- Because the valuation rests on durability, and moving from a growing perpetuity to no growth cut the letter's example from 25 times to 10 times after-tax earnings
- Because costs rise first
Show the answer
Answer: B.
The revenue consequence of a substitution can take years. The consequence for what the earnings are worth arrives as soon as the expectation changes.Sources
- Bristol-Myers Squibb Company, Form 10-K for the year ended 31 December 2025, filed 2026-02-11, accession 0000014272-26-000004: the product revenue table and total revenues.
- Berkshire Hathaway shareholder letter, 1991: the erosion of media economics, the three conditions of an economic franchise, and the valuation arithmetic for a growing perpetuity against normal earning power.
- Mauboussin, Callahan and Majd, Measuring the Moat, Credit Suisse, 1 November 2016: the aspartame case after the expiry of the European patent in 1987.
What this leaves out
- The Bristol Myers Squibb figures are product revenues as reported for 2025 and 2024, with the percentage changes as the filing states them. The filing attributes the declines to its own stated causes, and this lesson does not add to them.
- The four endings are this course's organisation of what the cited sources record. They are not an exhaustive list and not a prediction about any company.
- Nothing here is a view on Bristol Myers Squibb or on any security.